A popular traditional medicinal herb is Syzygium cumini. Its therapeutic qualities are a result of the plant’s phytochemical components. Study materials included S. cumini (Magnoliopsida: Myrtaceae) seeds, ethanol, and crude methanol extracts. The extract’s antimicrobial qualities against common bacterial strains were evaluated in this agar well using diffusion. Flavonoids, alkaloids, glycosides, steroids, phenols, saponins, terpenes, cardiac glycosides, and tannins are among the chemical classes that have been found in seed extracts through phytochemical analysis. Clear inhibitory effects of the extracts against clinical isolates are shown. Gram-negative and Gram-positive bacteria include Staphylococcus aureus and Salmonella typhi. It was found that the methanolic extract of the seed exhibited more antibacterial activity compared to the extracts obtained from the leaves and bark. The current study supports the use of several S. cumini seed extract as effective antimicrobial agents for the environmentally friendly and sustainable management of a variety of bacterial strains, but more research is needed before they can be applied in the field.

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