Abstract
Six-membered nitrogen containing heterocyclic bioactive molecules like quinazolines, and its derivatives have gained significant interest in recent years. Quinazolines have found to be an important base moiety in many of drugs used in the treatment of cancer and other diseases. Syntheses of quinazolines using green and sustainable methods have grabbed reasonable attention of researchers, to limit the use hazardous catalysts and reaction conditions. Among various methods, use of heterogenous eco-friendly nano-catalysts have emerged as an excellent approach for preparation of quinazolines. Nanoparticle based catalysts possess many advantages over conventional catalytic system since nano-catalyst provides high surface area for the rapid conversion into product even under mild reaction conditions and easily separated out from reaction mixture without following tedious work-up procedures. In this review we documented various nano-catalysts used for synthesis of biologically active quinazolines and their derivatives.
doi: 10.17756/nwj.2023-s5-078
Citation: Pathak S, Nair R, Mathur R, Shrivastava R. 2023. Synthesis of Quinazolines Scaffold Using Green and Sustainable Heterogenous Nano-catalysts. NanoWorld J 9(S5): S480-S486.
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