Carlo Ventura
Associate Editor for Regenerative Medicine

Claudio Ando Nicolini

Carlo Ventura received his M.D., the Ph.D. in Biochemistry and the Specialization in Cardiology from the University of Bologna, Italy. He spent several years at the Laboratory of Cardiovascular Sciences of the N.I.H./N.I.A. in Baltimore, USA. He is Full Professor of Molecular Biology and Director of the Experimental Cardiology Unit of the Institute of Cardiology at the University of Bologna, Italy. He is Scientific Director of (i) the “Stem Wave Institute for Tissue Healing (SWITH)” - Ettore Sansavini Health Science Foundation, and (ii) Gruppo Villa Maria (GVM) Care & Research (Lugo, Ravenna, Italy), (iii) the Division of Bologna of the National Institute of Biostructures and Biosystems (NIBB) (www.inbb.it), including the NIBB Research Units of Bologna, Firenze, and Siena, Italy, and (iiii) The NIBB National Laboratory of Molecular Biology, at the S. Orsola – Malpighi Hospital of the University of Bologna, Italy.

In 2011, he founded VID art|science (www.vidartscience.org), an international movement promoting transdisciplinary approaches in Arts and Sciences. VID art|science encourages the common journey of Artists and Scientists to bring about a consciousness shift towards recognizing the inherent unity of Arts and Sciences, exploring the avant-garde of scientific innovation to unravel how human Arts may speak to the innermost dynamics of our biology to reawaken our self-healing potential. At VID art|science Artists are evolving towards expressive forms autonomously inspired by a scientific landscape made of novel discoveries and paradigms.

He devoted his studies to the molecular dissection of myocardial cell growth and differentiation, discovering nuclear endorphin receptors and signaling responsible for stem cell cardiogenesis. He developed new molecules with differentiating and paracrine logics for cardiovascular repair. He discovered the ability of electromagnetic fields to enhance stem cell pluripotency, and afford direct reprogramming of human dermal skin fibroblasts to myocardial, neuronal and skeletal muscle lineages. He showed that properly conveyed electromagnetic fields were able to revert stem cell senescence, disclosing novel perspectives in regenerative medicine. He found that stem cells are extremely sensitive to acoustic vibrational signatures. These findings paved the way to the use of physical energy in stem cell science.

Areas of Expertise: Regenerative Medicine, Stem cells, use of physical energies (magnetic fields, nanomechanical vibrations, light) to orchestrate stem cell pluripotency, differentiation and paracrine behavior. Exosomes, as nanovescicles bearing pockets of information. Identification of naturally occurring molecules and development of synthetic agents with differentiating and paracrine “logics”, amenable for tissue regeneration. Use of nanoscience tools to monitor and/or affect stem cell dynamics, including atomic force microscopy (AFM) and Hyperspectral Imaging (HSI).

Keywords: Stem Cells, Regenerative Medicine, Tissue Regeneration, Precision Medicine, Aging, Reprogramming, Electromagnetic Fields, Sound, Light.

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