In Vitro Anticancer Activity of Green Synthesis Ruthenium Nanoparticle from Dictyota dichotoma Marine Algae

Mohamed Yacoob Syed Ali, Venkatraman Anuradha, Rajan Abishek, Nagarajan Yogananth and Harikrishan Sheeba
 

Abstract

Nanomedicine is the most revolutionized procedure to a greater extent in days to come. Among other nanoparticles Ruthenium compounds are well known for their high relevance as drug candidates, though they have very little in common with the already existing platinum-based drugs. By a rapid synthetic method Ruthenium nanoparticles were synthesized from Dictyota dichotoma marine algae and characterized for its efficiency against human cancer cell lines. The objective set for this study had been to prepare Ruthenium nanoparticles in a simple, cost effective and eco-friendly way unlike chemical procedures. We used the extract of Dictyota dichotoma as a reducing and capping agent. In the present study, it was observed that RuNPs induces a concentration dependent inhibition of cells. Hence RuNPs also offer the tendency of reduced toxicity and could be tolerated under in vivo method. By this method of preparation, the problems of environmental pollution were avoided.

Published on: December 13, 2017
doi: 10.17756/nwj.2017-049
Citation:  Ali MS, Anuradha V, Abishek R, Yogananth N, Sheeba H. 2017. In Vitro Anticancer Activity of Green Synthesis Ruthenium Nanoparticle from Dictyota dichotoma Marine Algae. NanoWorld J 3(4): 66-71.

Bitnami